NEOZYM
Extension of the catalytic promiscuity of artificial and natural metallo‑CAZymes toward non‑native reactivities
Context
Enzymes are increasingly recognized as catalysts for green and sustainable chemistry. Indeed, they operate in aqueous media and can significantly reduce the number of synthetic steps required in chemical synthesis. However, a major limitation lies in the catalytic scope of enzymes being restricted to the chemical functionalities conferred by the twenty natural amino acids.
Objectifves
The NeoZYM project has a dual aim: to create artificial metallo‑glycoenzymes and to extend the catalytic promiscuity of natural metalloenzymes.
Expected results
This highly innovative project aims to target industrial applications in the medium to long term, focusing on the synthesis of oligosaccharides and biomaterials, as well as the tailored development of artificial enzymes.
Target markets
- Oligosaccharides
- Biomaterials
- Artificial enzymes
Components involved
- UMR 792 TBI
- UMR 1163 BBF