BBF
Filamentous Fungi – Lignocellulosic Enzymes – White Biotechnology – Lignocellulose
The Component presentation
Research conducted at the Biodiversity and Fungal Biotechnology Unit (BBF) focuses on the ability of filamentous fungi to degrade complex polymers. The areas of study include both fundamental and applied research on the adaptation of fungi to a wide range of substrates and unfavorable environmental conditions, as well as the biochemical and structural determinants of enzymes active on natural and synthetic polymers that are resistant to degradation.
One of the objectives of this research is to characterize fungal enzymatic systems and propose biocatalysts for the valorization of plant biomass for chemistry and energy. The goal of this research is to develop bioprocesses based on renewable carbon resources as a substitute for fossil carbon in the context of a circular bioeconomy.
Research topics
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How do fungi adapt and respond to lignocellulosic substrates?
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How do fungal systems degrade recalcitrant polysccharides?
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How do fungi utilize phenolic compounds?
CIRM-CF Filamentous Fungi
CIRM-CF is a biological resource center dedicated to the preservation of filamentous fungi of interest to the agro-industry and their applications. The fungal strains originate from unique biotopes (temperate, tropical, or polluted industrial sites). This unique collection is ISO 9001 certified for the acquisition, authentication, preservation, and distribution of fungal resources.
PICHIA PASTORIS PROTEIN EXPRESS : 3PE
The 3PE platform relies on years of expertise and know-how, using original medium-throughput methodologies for the production of recombinant proteins. In this context, our platform offers various services: Gene cloning; Transformation in Pichia pastoris; Recombinant protein production at multiple scales; Automated protein purification (screening and/or production) ; Activity assays.
Success stories - OLEOINNOV
OléoInnov was founded in January 2019. Its origins lie in six years of research projects (2012–2018) between the UMR BBF and two key players in the French oilseed-protein sector: the Terres Inovia technical center for oilseeds and protein crops, and the Terres Univia inter-profession for vegetable oils and proteins. These projects aimed to develop sustainable processes for producing high-value molecules from rapeseed cake.
As a result of these research projects, two innovative processes were developed, enabling:
- The production of a biocatalyst that replaces harmful chemicals, thus benefiting both the environment and human health.
- The production of bio-based molecules with numerous pharmacological and cosmetic properties.
In 2019, Frédéric Fine (Terres Inovia), Elise Odinot, Anne Lomascolo (BBF Laboratory), and Jean-Claude Sigoillot (BBF Laboratory) were the driving forces behind the creation of OléoInnov, with the support of INRAE, Terres Inovia, Terres Univia, and the Impulse Inter-University Incubator.